Determinants of Spike Timing-Dependent Synaptic Plasticity
نویسندگان
چکیده
منابع مشابه
Determinants of Spike Timing-Dependent Synaptic Plasticity
Recent studies show that the precise timing of presynaptic inputs and postsynaptic action potentials influences the strength and sign of synaptic plasticity. In this issue of Neuron, Sjöström and colleagues (2001) determine how this so-called spike timing-dependent plasticity depends on the frequency and strength of the presynaptic inputs.
متن کاملSpike timing dependent plasticity: mechanisms, significance, and controversies
Long-term modification of synaptic strength is one of the basic mechanisms of memory formation and activity-dependent refinement of neural circuits. This idea was purposed by Hebb to provide a basis for the formation of a cell assembly. Repetitive correlated activity of pre-synaptic and post-synaptic neurons can induce long-lasting synaptic strength modification, the direction and extent of whi...
متن کاملSpike timing dependent plasticity: mechanisms, significance, and controversies
Long-term modification of synaptic strength is one of the basic mechanisms of memory formation and activity-dependent refinement of neural circuits. This idea was purposed by Hebb to provide a basis for the formation of a cell assembly. Repetitive correlated activity of pre-synaptic and post-synaptic neurons can induce long-lasting synaptic strength modification, the direction and extent of whi...
متن کاملSpike-timing-dependent synaptic plasticity and synaptic democracy in dendrites.
We explored in a computational study the effect of dendrites on excitatory synapses undergoing spike-timing-dependent plasticity (STDP), using both cylindrical dendritic models and reconstructed dendritic trees. We show that even if the initial strength, g(peak), of distal synapses is augmented in a location independent manner, the efficacy of distal synapses diminishes following STDP and proxi...
متن کاملSpike-timing dependent plasticity
Spike Timing Dependent Plasticity (STDP) is a temporally asymmetric form of Hebbian learning induced by tight temporal correlations between the spikes of preand postsynaptic neurons. As with other forms of synaptic plasticity, it is widely believed that it underlies learning and information storage in the brain, as well as the development and refinement of neuronal circuits during brain develop...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Neuron
سال: 2001
ISSN: 0896-6273
DOI: 10.1016/s0896-6273(01)00541-4